Menstruation and abnormal uterine bleeding:
- Development of a unique mouse model for endometrial breakdown and repair has enabled a paradigm shift in our understanding of abnormal uterine bleeding which will drive new strategies to limit menstrual disturbances.
- An Australia-wide clinical trial has identified new treatments for limiting the abnormal uterine bleeding associated with the use of implantable progestin-only contraceptives.
Pregnancy and implantation
- Discovery of a unique protease important for placental development. Studies to date suggest its detection in serum may provide a predictive indicator of early placental function (eg. pre-eclampsia).
- Identification of new functions for chemokines (previously known for their regulation of leukocytes) in trophoblast adhesion and migration.
New contraceptive targets for women
- Identification of a protease critical for uterine receptivity that also promotes HIV infectivity provides an option for a contraceptive with a dual action in limiting HIV infection in women.
- Demonstration that new long-acting inhibitors of specific cytokines can block development of uterine receptivity provides proof of principal that they could be used for contraceptive purposes in women.
Recent Awards to Group Members Dr Guiying Nie, Australian Academy of Science, JSPS Bilateral Program Award, 2005 Dr Christine White, Young Scientist of the Year Award, The Australian and British Council, 2005 Ms Natalie Hannan, selected to participate in “Fresh Science 2006” (16 selected of 87 nominations).
Staff Profiles
Professor Lois Salamonsen, Group Leader [pdf]
Dr Guiying Nie [pdf]
Dr Eva Dimitriadis [pdf]
Dr Naomi Morison [pdf]
Dr Lynette Kilpatrick [pdf]
Students [pdf]
|
Recent Awards