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| Research Trial: Researchers at Monash Medical Centre, Clayton in collaboration with the World Health Organisation are trialing a new male contraceptive method. We need healthy couples living in a stable relationship and not planning pregnancy for two years. more details >> |
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Media Release: 21 June 2006 Big bellied men wanted for testosterone study Prince Henry’s Institute in Melbourne is seeking healthy but overweight men to take part in a study on the effects of testosterone treatment on body fat and heart disease. Non-smokers, aged 40-70 years, are needed for a series of clinical trials to investigate the link between testosterone levels, fat and the risk of heart disease in ageing men. Dr Carolyn Allan and Professor Rob McLachlan from Prince Henry’s Institute have shown that men over the age of 55 with low testosterone may have a greater risk of heart attack. Men with extra abdominal fat are also at greater risk of developing cardiovascular disease. “We know that men with heart disease are likely to have low testosterone levels, but we don’t know which comes first – the heart disease or the low testosterone. “We now want to trial the effectiveness of testosterone treatment in men who are carrying extra abdominal fat,” said Dr Allan. Dr Allan believes testosterone treatment may be beneficial for ageing men with low levels of testosterone who are overweight and at risk of heart disease. “We have shown that if men lose weight, their testosterone levels increase. We also know that when men with a lot of abdominal fat are given testosterone, their fat decreases,” she said. The hormonal changes that occur in men as they age are often referred to as the ill-defined Andropause or Male Menopause. Testosterone levels in men decline by approximately 1-2% from the age of around 40 years. Testosterone deficiency affects one in 200 men under the age of 60 and increases with age. Low levels of testosterone can impact muscle mass, body composition, bone and reproductive function. Symptoms may include poor concentration, tiredness, irritability and a reduced sex drive. Non-smoking, healthy but overweight men aged 40-70 years who are interested in participating in the trial should contact: Anna Zamojska or Elise Forbes at Prince Henry’s Institute on 9594 3087 or 9594 3554. To arrange an interview with Dr Carolyn Allan, or a current testosterone trial participant, contact Andrew McCallum at Prince Henry’s Institute on 9594 4318 or 9594 4372
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