Prince Henry’s Institute

 

Ann Drummond

 

Appointments

• Adjunct Lecturer, Department of Biochemistry and Molecular Biology, Monash University

Profile

Dr Drummond completed her PhD studies in the area of testicular physiology. Her first appointment as an Assistant Lecturer in the Department of Biochemistry at Monash University, combined teaching and research and it was during this period that her research focus turned to regulation of ovarian function. In 1994, she joined PHI and since this time has pursued the roles of oestrogen and transforming growth factor-beta superfamily members in regulating ovarian follicle development.

 

Research Interests

Her current research focuses on the regulation of folliculogenesis with an emphasis on local control mechanisms. The results of these studies will lead to a better understanding of and treatments for infertility, premature menopause and ovarian cancer and facilitate the development of new contraceptives.

 

Expertise

Molecular assessment of the ovary, in vivo models of folliculogenesis

 

Current Research

• Hormonal regulation of folliculogenesis

• Ovarian phenotype of the Ikkβ conditional knockout mouse

• Role of ERβ in folliculogenesis

 

Service to the Scientific Community

• Editorial board, Journal of Endocrinology

• Editorial board, Reproduction

 

Selected Publications

Rosairo D,  Kuyznierewicz, I., Findlay J.K. and Drummond A.E. Transforming growth factor-β: its role in ovarian follicle development. Reproduction 136:799-809.2008

Drummond A.E., Tellbach M., Dyson M. and Findlay J.K. Fibroblast growth factor-9, a male sex determining factor, identified in the ovary.   Endocrinology, 148:3711-3721, 2007.

Drummond A. and Findlay JK.  Focus on TGF-beta signalling.  Editorial: Reproduction 132, 177-178, 2006

Drummond A.E. The role of steroids in follicular growth. Reprod. Biol. Endocrinol. 4:16, 2006.

Drummond A.E. TGF-beta signalling in the development of ovarian function. Cell and Tiss. Res. 322: 107-115, 2005.

Drummond AE, Dyson M, Le MT, Ethier J-F and Findlay JK.  Ovarian follicle populations of the rat express TGF-beta signalling pathways.  Molecular and Cellular Endocrinology 202, 53-57, 2003.

Kate Lakoski Loveland, Marilyn Bakker, Terri Meehan, Elizabeth Christy, Viktoria von Schönfeldt, Ann Drummond, and David de Kretser Expression of Bambi is widespread in juvenile and adult rat tissues and regulated in male germ cells. Endocrinology 144(9):4180-4186, 2003.

Jones, R.L., Salamonsen, L.A., Zhao, Y.C., Ethier, J-F., Drummond, A.E. and Findlay J.K. Expression of activin receptors, follistatin and betaglycan by human stromal cells: evidence for a role for activins during decidualisation. Mol. Human Reprod. 8: 363-374, 2002.

Britt KL, Kerr J, O'Donnell L, Jones MEE, Drummond AE, Davis SR, Simpson ER and Findlay JK.  Estrogen regulates development of the somatic cell phenotype in the eutherian ovary.  FASEB J 16:1389-1397, 2002

Drummond AE, Le MT, Ethier J-F and Findlay JK.  Expression and localization of activin receptors, Smads and betaglycan to the postnatal rat ovary.  Endocrinology 143: 1423-1433, 2002

Findlay JK, Drummond AE, Dyson ML, Baillie AJ, Robertson DM. and Ethier J-F. Recruitment and development of the preovulatory follicle; the roles of the transforming growth factor-beta superfamily.  Molecular & Cellular Endocrinology 191:35-43, 2002

Drummond AE, Britt KL, Dyson M, Jones MEE, Kerr JB, O'Donnell L, Simpson ER and Findlay JK.  Ovarian steroid receptors and their role in ovarian function.  Molecular and Cellular Endocrinology 191:27-33, 2002