Research Trial:
Researchers at Monash Medical Centre, Clayton in collaboration with the World Health Organisation are trialing a new male contraceptive method. We need healthy couples living in a stable relationship and not planning pregnancy for two years.
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Inhibin is a complex protein hormone produced in the ovary and the testis. Its primary role is to regulate the production of FSH by the pituitary, however studies suggest that inhibin may have other sites of action within the ovary and the testis, and in bone. We are in the process of identifying specific receptors for inhibin so that we can learn more about the roles of this hormone. Recent studies suggest that specific inhibin receptors may exist in the testis, indicating that inhibin may act directly to mediate testis function.

We are also investigating how inhibin production in the male is regulated. Specifically we are using cell culture models to investigate whether developing germ cells regulate inhibin production by the Sertoli cells, and whether germ cells themselves make inhibin. Such studies have relevance to the development of diagnostic tests for various forms of infertility.



















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